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Carbon monoxide (CO) is a colorless, odorless, and tasteless gas that exerts a number of biologic effects in a variety of different tissues and organs. 1, 2 Historically, CO was regarded as a poison because of the well-characterized tissue hypoxia and overt toxicity that result after exposure to high concentrations. 2 Classification of CO as a life-threatening toxin is certainly warranted ...
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19/07/2021· AbstractGeneral anesthesia has been unequivocally linked to abnormal development of the central nervous system, leading to neurocognitive impairments in laboratory models. In vitro and in vivo… Read Original Article: Does general anesthesia affect neurodevelopment in infants and children?
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09/12/2019· Read the full review for this Faculty Opinions recommended article: Does general anesthesia affect neurodevelopment in infants and children?
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Numerous preclinical evidence has confirmed that most commonly-used general anesthetics can affect neurodevelopment of young animals adversely, causing both structural defect of brain and cognitive impairment. However, it is unclear at present whether such effect would also occur to children exposed to general anesthesia in their early life.
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The possibility of anesthetic induced neurotoxicity occurring in children has led to concerns about the safety of pediatric anesthesia. A spectrum of behavioral changes has been documented after general anesthetic exposure in young children, including emergence delirium, which may be evidence of toxicity.
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Many people find it difficult to sleep in bright light. However, as late as the 1980s, harsh lighting was most often used in neonatal intensive care units (NICUs), 1 negatively affecting our most vulnerable patients. Today, we know that when it comes to premature babies, light is a very complex matter.
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AbstractA potentially life-threatening emergency in ENT practice is the aspiration of tracheobronchial foreign body. This commonly affects young children and requires early extraction. Successful removal provides immediate relief. However procedural complications can cause devastating morbidity like anoxic encephalopathy or instant death.
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Does general anesthesia affect neurodevelopment in infants and children? Abstract General anesthesia has been unequivocally linked to abnormal development of the central nervous system, leading to neurocognitive impairments in laboratory models.
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Request PDF | On Jan 1, 2015, J.H. Lee and others published Neurodevelopmental implications of the general anesthesia in neonate and infants …
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Few studies of how exposure of children to anesthesia may affect neurodevelopment employ comprehensive neuropsychological assessments. This study tested the hypothesis that exposure to multiple, but not single, procedures requiring anesthesia before age 3 yr is associated with adverse neurodevelopmental outcomes.
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24/06/2019· Whether general anesthesia in neonates impairs long-term neurodevelopment and cognition remains uncertain. In an international randomized, controlled trial in 28 neonatal centers, investigators evaluated intelligence and other neurodevelopment measures at age 5 years in 722 infants (mostly boys) who underwent herniorrhaphy during infancy with use of …
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Effect of therapeutic suggestions during general anaesthesia on postoperative pain and opioid use: multicentre randomised controlled trial. ... Does general anesthesia affect neurodevelopment in infants and children? BMJ. 2019;367:l6459. >> Share: RIMMER A
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19/08/2016· FROM THE JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY About 10,000 newborns receive general anesthesia for congenital heart defects every year, and the more exposure they have to inhaled anesthetic agents, the greater effect it may have on their neurologic development, investigators at Children’s Hospital of Philadelphia reported in a study…
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Does general anesthesia affect neurodevelopment in infants and children? Mary Ellen McCann,1,2 Sulpicio G Soriano 1,2 1Department of Anesthesia, Harvard Medical School, Boston, MA, USA 2Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children’s Hospital, Boston, MA, USA Correspondence to: S Soriano Sulpicio.Soriano ...
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29/11/2021· Although recent clinical studies agree that anesthetic exposure in young children does not affect general cognition, several studies have suggested significant changes in specific developmental domains such as motor and social performance (Warner et al., 2018; Walkden et al., 2020; Ing et al., 2021). Also, the neurotoxic effects of prolonged or multiple anesthetic …
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Repeated or lengthy use of general anesthetic and sedation drugs in children younger than 3 years or in pregnant women during their third trimester may affect children''s developing brains ...
Chat Online09/12/2019· Practitioners and families should be reassured that although general anesthetics have the potential to induce neurotoxicity, very little clinical evidence exists to support this. Does general anesthesia affect neurodevelopment in infants and children? | The BMJ
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Request PDF | On Jan 1, 2015, J.H. Lee and others published Neurodevelopmental implications of the general anesthesia in neonate and infants …
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18/10/2016· Every year, millions of patients receive general anaesthesia for surgery or diagnostic procedures, and there is a growing concern that anaesthetic drugs might exert long-term effects on the CNS ...
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The possibility of anesthetic induced neurotoxicity occurring in children has led to concerns about the safety of pediatric anesthesia. A spectrum of behavioral changes has been documented after general anesthetic exposure in young children, including emergence delirium, which may be evidence of toxicity.
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